Ivacaftor Study

Are you Eligible?

Inclusion Criteria:

  • Confirmed diagnosis of CF
  • Individuals age ≥ 6y
  • Starting ivacaftor

Exclusion Criteria:

  • Established diagnosis of non-CF diabetes (i.e. T1D) or CFRD with fasting hyperglycemia, (fasting glucose > 126 mg/dL)
  • History of pancreatitis within last year
  • Prior lung or liver transplant
  • Severe CF liver disease, as defined by presence of portal hypertension
  • Fundoplication-related dumping syndrome
  • Medical co-morbidities that are not CF-related or are unstable
  • Acute CF pulmonary exacerbation within 4 weeks prior to study procedures.
  • Treatment with oral or intravenous corticosteroids within 4 weeks of enrollment
  • Hemoglobin <10 g/dL
  • Abnormal renal function